Selektīvie androgēnu receptoru modulatori

Selektīvie androgēnu receptoru modulatori jeb SARM ir jauna androgēnu receptoru ligandu klase. To pielietojums pielīdzināms androgēniem medikamentiem, taču to darbība ir daudz selektīvāka, sniedzot plašākas lietošanas iespējas, atšķirībā no anaboliskajiem steroīdiem, kuru lietošanu ierobežo tiesiski regulējumi.^[1]^[2]

Atsauces

↑ "Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit". Journal of Medicinal Chemistry 52 (12): 3597–617. June 2009. doi:10.1021/jm900280m. PMID 19432422.
↑ Ramesh Narayanan. “Development of Selective Androgen Receptor Modulators (SARMs).” (Molecular and Cellular Endocrinology, vol. 465 izd.). Elsevier BV, April 2018. 134–142. lpp.

[pmid19432422-1] "Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit". Journal of Medicinal Chemistry 52 (12): 3597–617. June 2009. doi:10.1021/jm900280m. PMID 19432422.

[2] Ramesh Narayanan. “Development of Selective Androgen Receptor Modulators (SARMs).” (Molecular and Cellular Endocrinology, vol. 465 izd.). Elsevier BV, April 2018. 134–142. lpp.

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